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KMID : 0385920150260050480
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Journal of the Korean Society of Emergency Medicine
2015 Volume.26 No. 5 p.480 ~ p.482
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A Case of Diabetic Ketoacidosis with Refractory Metabolic Acidosis Successfully Treated with Continuous Hemodiafiltration
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Lee Seong-Hee
Kim Byeong-Gwan
Cho A-Young
Kim Sang-Sun
Shin Hong-Shik
Kim Jeong-Gwan
Sun In-O
Lee Kwang-Young
Yoon Hyun-Ju
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Abstract
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Diabetic ketoacidosis (DKA) is a complex medical disorder characterized by abnormalities in electrolyte, acid-base, and volume status. Metabolic acidosis in mild and moderate DKA is corrected with insulin therapy. Bicarbonate therapy may be indicated in cases of severe metabolic acidosis, however the use of bicarbonate in severe DKA is controversial due to a lack of prospective randomized studies. Renal replacement therapy can be used for correction of systemic acidemia. Continuous renal replacement therapy (CRRT) is used in patients who are too hemodynamically unstable to tolerate conventional hemodialysis, but has also been used in treatment of patients with severe DKA. CRRT has never been used previously in DKA patients with refractory metabolic acidosis in Korea. Here, we describe the successful treatment of a DKA patient with refractory metabolic acidosis with CRRT.
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KEYWORD
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Diabetic ketoacidosis, Hemodiafiltration, Renal replacement therapy
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